Amlodipine

Amlodipine is a medicine called a calcium channel blocker. It works by relaxing and widening the blood vessels, which lowers blood pressure and improves blood flow [1].

It is used to treat high blood pressure and to help prevent chest pain caused by angina [1]. It usually comes as tablets or a liquid and is available only on prescription [1].

• Amlodipine is usually taken once a day and is often needed long term [1].
• It can be taken at any time of day, but try to take it at the same time each day [1].
• Do not stop taking it suddenly, as this could make things worse — speak to a doctor first [1].
• Swollen ankles and headaches are among the more common side effects [1].

Amlodipine can be taken by most adults and by children over 6, but it does not suit everyone [1]. It may not be suitable if you have had an allergic reaction to it, have very low blood pressure, certain heart conditions such as heart failure or heart valve problems, or have recently had a heart attack [1]. It is not usually recommended in pregnancy or while breastfeeding [1]. Your prescriber will check it is right for you.

Take amlodipine as your prescriber tells you and as set out on the label — usually once a day, with or without food [1]. Taking it at the same time each day helps you remember it [1]. If you miss a dose, take it when you remember unless it is nearly time for the next one; do not take two doses together [1]. Keep taking it even if you feel well, unless your doctor advises otherwise [1].

Common side effects can include swollen ankles or feet, headaches, dizziness, flushing and feeling tired, and these often ease as your body gets used to the medicine [1]. Tell a doctor if side effects trouble you or do not go away [1]. Get urgent medical help for signs of a serious reaction, such as fainting, a very fast heartbeat or a severe allergic reaction [1].

Amlodipine can interact with some medicines, including the statin simvastatin, certain other blood pressure medicines, some antibiotics and antifungals, and the herbal remedy St John's wort [1]. It is also best to avoid grapefruit juice while taking it [1]. Tell a pharmacist or doctor what else you take, including over-the-counter and herbal products, before starting it [1].

Suspected side effects from amlodipine can be reported to the MHRA through the Yellow Card scheme, which helps monitor medicine safety in the UK [2]. Seek medical help for any serious reaction as well as reporting it.