Ramipril

Ramipril is a medicine called an ACE inhibitor. It works by relaxing and widening blood vessels, which makes it easier for the heart to pump blood around the body [1].

It is used to treat high blood pressure and heart failure, and it may be given after a heart attack; it can also help protect the kidneys in some people [1]. It usually comes as tablets or capsules and is available only on prescription [1].

• The first dose can make some people feel dizzy, so it is sometimes taken at bedtime to start with [1].
• A common side effect is a dry, tickly cough that does not go away [1].
• You may need blood tests to check your kidneys and salts before starting and during treatment [1].
• Keep taking it even if you feel well, unless a doctor tells you to stop [1].

Ramipril can be taken by many adults, but it does not suit everyone [1]. It may not be suitable if you have had an allergic reaction to it or to other ACE inhibitors, if you have certain kidney or heart conditions, or if you are pregnant or trying to become pregnant [1]. Tell your prescriber about your health and any other medicines so they can check it is right for you [1].

Take ramipril as your prescriber tells you and as set out on the label — the dose is often started low and increased gradually [1]. It can be taken with or without food, usually at the same time each day [1]. If you get diarrhoea or vomiting, or become very dehydrated, contact your doctor, as ramipril may need to be paused [1]. Do not stop taking it suddenly without advice [1].

Common side effects can include a dry cough, dizziness (especially when standing up), headaches and mild digestive upsets, and these often settle as your body adjusts [1]. Get urgent medical help if you have signs of a serious reaction, such as swelling of the face, lips or throat, difficulty breathing, or symptoms that suggest a problem with your kidneys, liver or blood [1].

Ramipril can interact with several medicines, including anti-inflammatory painkillers such as ibuprofen, some other blood pressure medicines and water tablets, potassium supplements and lithium [1]. Tell a pharmacist or doctor what else you take, including over-the-counter and herbal products, before starting it [1].

You can report a suspected side effect from ramipril to the MHRA through the Yellow Card scheme, which helps monitor medicine safety in the UK [2]. Seek medical help for any serious reaction as well as reporting it.